In 2017 Burning Rock entered a partnership with Agilent Technologies to co-develop an IVD system that could help widen patient access to NGS testing across China. The rationale was simple, a sophisticated NGS workflow requires considerable resources that pose issues for hospitals and laboratories alike.
The library construction preparation phase is well regarded as the most labor-intensive portion of the NGS workflow, requiring both manual effort and time, apart from being a relatively error-prone step. NGS operators need to be highly trained and a system of coordination must be established to ensure samples are passed along the workflow in a timely manner.
The cumbersome nature of NGS workflow can be incredibly difficult for hospitals to manage concurrently with standard pathology proceedings, especially when the number of patients is high. Pairing Burning Rock’s proprietary chemistry with Agilent’s technological expertise, the Magnis BR was conceived with the goal of automating the entire NGS process and providing the China market with the first approved IVD companion diagnostic.